Propranolol is a beta blocker given to ease the pain of patients with episodes of unstable angina. A new drug for the treatment of this disease is tested on 30 pairs of patients who are matched on a one-to-one basis according to age, sex, and clinical condition and are assessed as to the severity of their pain. Suppose that in 15 pairs of patients, the patient with the new drug has less pain; and in l0 pairs of patients, the patient with propranolol has less pain; and in 5 pairs of patients, the pain is about the same with the two drugs.
Suppose normality is not assumed. What nonparametric test can be used to compare total heart weight of males with left-heart disease with that of normal males?
Can you Implement the test above and report a p-value.
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